Severe vestibular dysfunction and altered vestibular innervation in mice lacking prosaposin
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چکیده
منابع مشابه
Progressive deafness and altered cochlear innervation in knock-out mice lacking prosaposin.
After a yeast two-hybrid screen identified prosaposin as a potential interacting protein with the nicotinic acetylcholine receptor (nAChR) subunit alpha10, studies were performed to characterize prosaposin in the normal rodent inner ear. Prosaposin demonstrates diffuse organ of Corti expression at birth, with gradual localization to the inner hair cells (IHCs) and its supporting cells, inner pi...
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BACKGROUND Chronic vestibular dysfunction is a frustrating problem in the elderly and can have a tremendous impact on their life, but only a few studies are available. Vestibular rehabilitation therapy (VRT) is an important therapeutic option for the neuro-otologist in treating patients with significant balance deficits. OBJECTIVES The purpose of this study was to assess the effect of vestibu...
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ژورنال
عنوان ژورنال: Neuroscience Research
سال: 2012
ISSN: 0168-0102
DOI: 10.1016/j.neures.2012.01.007